Facilities and Equipment
Auritec 's laboratories are housed inside the Oak Crest Institute of Science, a 7,000 ft2 open-plan laboratory space. Auritec rents about half of the square footage and has access to all of Oak Crest's equipment via a fee for service agreement.
Two large, central laboratory spaces include a wet-lab and primary research areas. Shared wet-lab and microbiology resources include four chemical fume hoods, two level 3 biosafety laminar-flow hoods, recirculating chilled water supply, on-line deionized water system (1MW and >18 MW), vacuum lines, inert atmosphere glovebox with recirculating purifier, refrigeration and freezing (4°C, 0°C, -20°C, -30°C, -80°C), autoclave, incubators, and liquid nitrogen supply. The Instrumentation Facility and Laser Laboratory are in dedicated spaces separated from the open-plan wet lab.
The following major research equipment is available at the Oak Crest Laboratory facility:
Spectroscopy:
FTIR spectrometer (Nicolet Magna-IR 560)
UV-vis spectrometers (HP 8452A, Cary 50Bio, Shimadzu UV2104PC, and Ocean Optics S2000 & SD2000)
Fluorescence spectrometers (SPEX Fluorolog and Hitachi FL4500)
Raman spectrometer (Chromex 250is imaging spectrograph/Princeton Instruments CCD camera; Ar+, CW Nd:YAG, and diode laser sources)
Chromatography (located in ~280 ft2 Instrumentation Laboratory):
HPLC (two Hewlett Packard Ti Series 1050 HPLCs with diode array UV-vis and fluoresc. detection)
LC-MS (one 1050 LC coupled to Sciex API 100 single quadrupole mass spectrometer)
IC (Dionex GP40 with UV-vis and conductivity detection)
GC (Hewlett-Packard 5890 Series II GC with FID & NPD detectors, HP 5890 Series II with FID & TCD detectors)
GC/MS (Hewlett-Packard Model 7890 gas chromatograph with a Model 5975C mass selective detector and a Model G1888 network headspace sampler and HP 5890 Series II GC with HP 5972 Series mass selective detector)
Electrochemistry:
Potentiostat/Galvanostats (EG&G PAR VersaStat and EG&G PAR 173/175) for cyclic voltammetry and other electrochemical experiments; Custom control software (LabView-based) written in house
Microscopy:
Light microscope with CCD camera
Epifluorescence microscope (Nikon Microphot-SA) with CCD camera
Laser Laboratory (located in two rooms totaling ~300 ft2):
Nanosecond fluorescence lifetime and transient-absorbance spectroscopy, laser-induced breakdown spectroscopy, Raman and resonance Raman spectroscopy
Equipment: CEO diode-pumped Nd:YAG laser (20 mJ/pulse), Continuum flashlamp-pumped Nd:YAG laser (200mJ/pulse), boadly tunable OPO (420-2000 nm), ns-pulsed Ti:sapphire laser, fiber and direct pumped Nd:YAG microlasers; UV, visible, and mid-IR monochromators; PMT, APD, and intensified gated-CCD (Andor iStar DH720) detectors; Stanford Research SR400 Photon Counter, Tektronix TDS5004 digital oscilloscope for data acquisition; 4 optical tables
Auritec Pharmaceuticals also owns the following equipment:
Ten USP type II dissolution systems manufactured by VanKel and Distek; a Zymark Multidose G3 autosampler; digital microscope; Spectronic 1201 UV/Vis spectrophotometer; HP UV/Vis spectrophotometer; a particle size counter; laminar flow hood; Carver press; centrifuge; lab oven and refrigerator; Harvard Navicyte 6 cell vertical Ussing chamber; Perkins – Elmer CSC-2 Differential Scanning Calorimeter; and a Vector Mini Wurster.